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应用紫外分光光度法对10名喘息型慢性支气管炎伴有肺气肿、肺心病的老年患者一次口服氨茶喊200mg后的药代动力学进行了研究。结果表明患者体内药物处呈一室模型,消除半衰期为11.60±4.16h,比文献[1]报道的健康老人的消除半衰期(T1/2)有明显延长。
The pharmacokinetics of 10 ammonia aminophylline 200 mg once oral administration in elderly patients with wheezing chronic bronchitis accompanied by emphysema and pulmonary heart disease were studied by ultraviolet spectrophotometry. The results showed that the drug in the patient showed a one-compartment model with a half-life of 11.60 ± 4.16h, which was significantly longer than that of the healthy elderly (T1 / 2) reported in [1].