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目的:探讨高渗葡萄糖溶液治疗流行性出血热(EHF)的疗效.方法:用高渗葡萄糖溶液治疗EHF232例,并以平衡盐液治疗EHF230例作对照.结果:高渗葡萄糖溶液组患者的水肿、低血压休克的持续时间均短于平衡盐液组[(6±2对7±2)d,(17±5对21±6)h],氮质血症轻于平衡业液组[血尿素氨(27±9)mmol/L对(29±10)mmol/L,肌酐(587±104)μmol/L对(600±98)μmol/L];并发症的发生率和病死率也低于平衡盐液组(分别为26.7％对55.7％,9.5％对15.7％).结论:以高渗葡萄糖溶液治疗EHF优于平衡盐液.","Objective:To study the efficacy of hypertonic glucose solution (HGS) in the treatment of epidemichemorrhagic fever (EHF). Methods: In this randomized, controlled trial, patients with EHF were treated withHGS or Ringer solution (RS), respectively, as fluid therapy. Results: Duration of edema and hypotension shockin patients treated with HGS were shorter than those treated with RS [ (6± 2) vs (7± 2) d and (17±5) vs (21 ±6)h, respectively ]. Blood urea nitrogen and creatinine in patients treated with HGS were also lower than those treatedwith RS [ (27 ±9 ) vs (29±10) mmol/L and (587±104 ) vs (600±98)μmol/L]. Both the incidence of complicationsand the mortality rate in patients treated with HGS were lower than those in RS-treated Ones (26. 7% vs 55. 7 % and9. 5 % vs 15. 7% ). Conclusion: Treatment of EHF with HGS as fluid therapy is superior to treatment with RS.