论文部分内容阅读
本文报告12例长期的弥漫型甲状腺机能亢进(简称甲亢)用碳酸锂单独治疗6个月。其中,女性9例,男性3例。平均年龄39岁(20～55岁)。病程2～13年。9例系停用硫脲类药物后复发,2例系甲状腺大部切除术后,1例系碘~(131)治疗后9个月仍未缓解。碳酸锂剂量是每日800或1200毫克,1次服用,使其血清锂浓度达0.5～1.5毫当量/升。 12例中11例对此药耐受良好,只有很轻微的副作用,均在治疗开始时发生,仅持续数日。1例于用药后3周停药。副作用有恶心、颤抖、头痛等。
This article reports 12 cases of long-term diffuse hyperthyroidism (referred to as hyperthyroidism) with lithium carbonate alone for 6 months. Among them, 9 were female and 3 were male. The average age is 39 years old (20 to 55 years old). Course of 2 to 13 years. Nine cases relapsed after discontinuation of thioureas, two cases were treated by partial thyroidectomy. One case of iodine 131 was not relieved at 9 months after treatment. Lithium carbonate dosage is 800 or 1200 mg daily, taking once, so that the serum lithium concentration of 0.5 to 1.5 meq / liter. Eleven of the 12 patients were well tolerated and had only mild side effects, both of which occurred at the start of the treatment, lasting only a few days. One patient discontinued 3 weeks after treatment. Side effects are nausea, trembling, headache and so on.