Refractory gastric ulcer with abundant IgG4-positive plasma cell infiltration: A case report

• 作 者: Takayoshi Fujita Takafumi Ando Masatoshi Sakakibara Waki Hosoda Hidemi Goto
• 机 构: Department of Gastroenterology,Aichi Cancer Center Aichi Hospital,Okazaki City,Aichi 444-0011,Japan,
• 出 处: World Journal of Gastroenterology
• 发表日期: 2010年17期
• 关键词: IgG infiltration autoimmune manifestation sclerosing abundant refractory Refract

We describe a 77-year-old man with refractory gastric ulcer that worsened after Helicobacter pylori eradication therapy.Pathology showed marked infiltration of IgG4-positive plasma cells in the gastric lesions,which led us to suspect IgG4-related sclerosing disease.To the best of our knowledge,this is the first report of IgG4-related gastric ulcer without the main manifestation of autoimmune pancreatitis.

We describe a 77-year-old man with refractory gastric ulcer that worsened after Helicobacter pylori eradication therapy. Pathology showed marked infiltration of IgG4-positive plasma cells in the gastric lesions, which led us to suspect IgG4-related sclerosing disease. To the best of our knowledge, this is the first report of IgG4-related gastric ulcer without the main manifestation of autoimmune pancreatitis.