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绝经后妇女雌激素缺乏与细胞学的变化,确定了女性下泌尿道是雌激素的敏感组织。泌尿系症状多发生在更年期之初,尤在绝经后头5年。雌激素适合治疗早期泌尿系症状,对因纤维化和狭窄形成的较晚症状效用不大。Rud(1980)曾用口服4-8 mg高剂量雌二醇治疗绝经后应力性尿失禁,70%的患者改善了症状。口服外源性雌激素大抵被机体代谢成雌酮。有报导称阴道雌激素霜后其尿中雌激素排出量和血浆雌酮水平与口服者相类似。本文测定了绝经后患者静止、用力时的尿道压力侧面图估
Postmenopausal women estrogen deficiency and cytology changes, determine the female urinary tract is estrogen sensitive tissue. Urinary symptoms occur at the beginning of menopause, especially in the first 5 years after menopause. Estrogen is suitable for the treatment of early urological symptoms and is less potent for later symptoms of fibrosis and stenosis. Rud (1980) used 4-8 mg of high-dose oestradiol orally to treat postmenopausal stress urinary incontinence, and 70% of patients improved their symptoms. Oral estrogen is probably metabolized to estrone by the body. It is reported that vaginal estrogen cream after urinary estrogen excretion and plasma estrone levels and oral similar. This paper measured the postmenopausal patients at rest, when forced urethral pressure profile map