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近年来有人提出使细菌胞壁裂解的抗生素能导致内毒素血症和脓毒性休克,但缺乏完整的动物实验来研究腹内感染时抗生素的应用与TNF释放间的关系。本文检测两种假设:(1)腹内感染期间应用抗生素能引起全身TNF值显著增高。
In recent years, it has been proposed that antibiotics that cause bacterial cell wall lysis lead to endotoxemia and septic shock, but there is a lack of a complete animal experiment to study the relationship between antibiotic use and TNF release during intra-abdominal infections. This article examines two hypotheses: (1) The use of antibiotics during an intra-abdominal infection can cause a significant increase in systemic TNF.