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腹部感染性疾病的手术治疗,由于脓、消化道内容物不同程度的污染,致使术后感染率很高,单纯性阑尾炎术后的切口感染率为1～8%,化脓性、坏疽性为11～24%,穿孔性为23～60%。全身应用抗生素,在病灶局部不易达到有效的治疗浓度,因此,病灶局部直接用药是合理的。经调查分析,外科手术(尤其是腹内感染)的厌氧菌检出率很高,且大多数是需氧菌和厌氧菌的混合性感染。我们配制了含有氯霉素的复方甲硝唑液(含氯霉素0.25%,甲硝唑0.2%,氯化钠0.9%),用于腹部外科胃肠、脏器穿孔,肝胆等手术冲洗。自
Surgical treatment of infectious diseases of the abdomen, due to varying degrees of pus and digestive tract contamination, resulting in a high postoperative infection rate, incision infection rate of simple appendicitis postoperative infection rate of 1 to 8%, purulent, gangrenous 11 ~ 24%, perforation is 23 ~ 60%. Systemic antibiotics, lesions in the local hard-to-reach effective therapeutic concentration, therefore, the local administration of lesions is reasonable. The investigation and analysis, surgical (especially intra-abdominal infection) anaerobic detection rate is high, and most are mixed infections of aerobic and anaerobic bacteria. We prepared a compound metronidazole solution containing chloramphenicol (containing 0.25% chloramphenicol, metronidazole 0.2%, sodium chloride 0.9%) for abdominal surgery gastrointestinal, organ perforation, liver and gallbladder and other surgical irrigation. from