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作者用一种能保护引入体内的抗原免受酶降解的微载体,成功地增强了经胃管给药的实验大鼠对掺入的可溶性抗原的免疫应答.100mg卵白蛋白、475mg丙烯酰胺和25mg双丙烯酰胺溶解后加过硫酸氨,并与100mg Pluronic F68的氯仿-甲苯溶液混合制成油包水乳胶,最后加250μl四甲基乙烯二胺,使聚合成微粒体,颗粒大小平均为2.55μm.首先给24只大鼠腹腔注射5mg卵
Using a microcarrier that protects the antigen introduced into the body from enzymatic degradation, the authors succeeded in enhancing the immune response of the experimental rats administered with gastric tubes to the incorporated soluble antigen: 100 mg ovalbumin, 475 mg acrylamide and 25 mg Bisacrylamide was dissolved in ammonium persulfate and mixed with 100 mg of Pluronic F68 in chloroform-toluene to prepare a water-in-oil emulsion. Finally, 250 μl of tetramethylethylenediamine was added to polymerize into microsomes with an average particle size of 2.55 μm Twenty-four rats were injected intraperitoneally with 5 mg of eggs