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目的:研究分析沙美特罗替卡松粉吸入剂联合地氯雷他定治疗咳嗽变异性哮喘的临床疗效。方法:将在我院2014年3月-2015年3月期间接受治疗的100例咳嗽变异性哮喘患者,按照随机数字的方法分为对照组和研究组,两组各分50例患者,其中对照组给予沙美特罗替卡松粉吸入剂进行治疗,研究组在对照组基础上给予地氯雷他定进行治疗,比较两组患者治疗后临床效果。结果:治疗后对照组总有效率74%,研究组90%,两组患者治疗后的总有效率相比其差异明显,统计学上有意义(P<0.05),治疗前后日、夜间咳嗽症状积分有明显变化,而且对照组积分变化明显低于研究组,两组比较差其异显著,具有统计学意义(P<0.05),患者均为发现明显不良反应。结论:采用沙美特罗替卡松粉吸入剂联合地氯雷他定治疗咳嗽变异性哮喘效果显著,有效改善患者咳嗽、哮喘症状,安全性高,值得临床广泛推广应用。
Objective: To study the clinical effect of salmeterol and fluticasone powder inhalation combined with desloratadine on cough variant asthma. Methods: One hundred patients with cough variant asthma who were treated in our hospital from March 2014 to March 2015 were divided into control group and study group according to the random number method. There were 50 patients in each group, Group received salmeterol fluticasone powder inhaler for treatment, the study group was treated with desloratadine on the basis of the control group, the clinical efficacy of the two groups were compared. Results: After treatment, the total effective rate was 74% in the control group and 90% in the study group. The total effective rate of the two groups after treatment was statistically significant (P <0.05), and the cough symptom There were significant changes in the scores, but the changes in the scores of the control group were significantly lower than those of the study group. The differences between the two groups were significant and statistically significant (P <0.05). All patients were found to have significant adverse reactions. Conclusion: Salmeterol tromethamine powder inhalation combined with desloratadine treatment of cough variant asthma significant effect, effectively improve the patients cough, asthma symptoms, high safety, it is widely used in clinical practice.