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目的:研究肺间质纤维化合并肺气肿综合征患者的临床特点。方法:选取本院在2012年4月至2014年4月期间收治的89例肺间质纤维化合并肺气肿患者作为研究对象,本次研究的89例患者却确诊为肺间质纤维化合并肺气肿,对患者的临床症状、肺功能以及影像学特征进行研究。结果:肺间质纤维化合并肺气肿多发于老年男性,且患者大多有长时间吸烟的习惯,通过血气分析发现患者多有低氧血症,采用HRCT能够高效、准确的诊断肺间质纤维化合并肺气肿。肺间质纤维化合并肺气肿患者的临床特征主要表现为双上肺肺气肿,在肺大疱和双下肺靠近胸膜的位置发生肺间质纤维化性的病变。通过肺功能检测可发现患者多存在混合型通气功能障碍,患者的弥散功能下降,患者呼吸困难。另外,本次研究中部分患者合并肺动脉高压以及恶性肺部肿瘤等。结论:肺间质纤维化与肺气肿是相对独立的两种疾病,但经常会发生在同一患者,该疾病患者通常年龄较大,病情也较为严重,难以进行肺功能和支气管镜的检查,而HRCT是重要的检查手段,临床医生要根据患者的临床症状结合检查结果进行诊断和治疗。
Objective: To study the clinical features of patients with pulmonary fibrosis complicated with emphysematous syndrome. Methods: A total of 89 patients with pulmonary interstitial fibrosis complicated with emphysema admitted from April 2012 to April 2014 in our hospital were enrolled in this study. 89 patients in this study were diagnosed as pulmonary fibrosis Emphysema, the patient’s clinical symptoms, lung function and imaging features were studied. Results: Pulmonary interstitial fibrosis complicated with emphysema was more common in elderly men. Most of the patients had the habit of smoking for a long time. Hypoxemia was found in most patients by blood gas analysis. Using HRCT to diagnose pulmonary interstitial fibrosis efficiently and accurately Combined with emphysema. The clinical features of patients with pulmonary fibrosis complicated with emphysema mainly manifested as double upper pulmonary emphysema, lung bullae and double lower lung near the pleura of pulmonary interstitial fibrosis occurs lesions. Pulmonary function tests found that there are many mixed ventilation dysfunction in patients with diffuse decline in patients with dyspnea in patients. In addition, some patients in this study with pulmonary hypertension and malignant lung tumors. Conclusions: Interstitial fibrosis and emphysema are relatively independent diseases, but often occur in the same patient. The patients are usually older and have more severe illness. Therefore, it is difficult to perform pulmonary function tests and bronchoscopy. The HRCT is an important means of examination, clinicians according to the clinical symptoms of patients combined with the results of the diagnosis and treatment.