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吡喹酮对急性血吸虫病发热影响有3个特点:(1)服药当天体温可明显升高;(2)疗程开始1-3d,发热可暂时抑制和下降;(3)疗程后轻型尚需数日、重型要10d左右才能退热。经临床验证选用了80-100mg/kg,2d疗法不仅同样能改善或消除症状、体征,而疗效有明显提高。常规6d疗法可考虑缩短疗程,增加分次剂量,提高疗效。此疗法较适合急性血吸虫病中重型患者的治疗。
Praziquantel on the impact of acute schistosomiasis fever has three characteristics: (1) on the day of taking the body temperature can be significantly increased; (2) 1-3d, the treatment of fever can be temporarily inhibited and decreased; (3) Day, heavy duty to about 10d to heat. The clinical validation of the selected 80-100mg / kg, 2d therapy not only can also improve or eliminate symptoms and signs, and the efficacy was significantly improved. Conventional 6d therapy can be considered to shorten the course of treatment, increase the sub-dose, improve efficacy. This therapy is more suitable for the treatment of severe patients with acute schistosomiasis.