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目的:探讨宫颈电环切除术(LEEP)在宫颈上皮内瘤变(CIN)诊断、治疗中的作用。方法:2005年1月~2007年12月,采用LEEP对98例CIN患者进行诊断和治疗,采用自身对照法对其疗效及病理检查进行回顾性分析。结果:本研究中,98例患者LEEP术后病理诊断结果,CINI级40例(40.82%);CINⅡ级35例(35.71%),CINⅢ级20例(20.41%,包括宫颈原位癌1例);宫颈早期浸润癌3例(3.06%)。98例患者术前进行阴道镜下多点活检,将病理检查结果进行对比,完全符合者88例(89.80%)。术后一般无出血或仅极少许血性分泌物。术后3~6个月复查宫颈液基薄层细胞学检查(TCT)均为正常或炎症。结论:宫颈电环切是宫颈上皮内瘤样变的一种重要诊断与治疗方法,对治疗宫颈良性病变具有极高的临床价值。
Objective: To investigate the role of cervical electrocorticoid excision (LEEP) in the diagnosis and treatment of cervical intraepithelial neoplasia (CIN). Methods: From January 2005 to December 2007, 98 cases of CIN were diagnosed and treated by LEEP. The curative effect and pathological examination were retrospectively analyzed by self-control method. Results: The pathological diagnosis of LEEP in 98 patients was 40 (40.82%) with CINI and 35 (35.71%) with CIN II and 20 (21.41%) with CINⅢ, Cervical early invasive carcinoma in 3 cases (3.06%). Ninety-eight patients underwent colposcopy multi-point biopsy before surgery. The pathological findings were compared and 88 patients (89.80%) were fully matched. No bleeding after surgery or only a very small amount of bloody discharge. 3 to 6 months after the review of cervical liquid-based thin-layer cytology (TCT) were normal or inflammatory. Conclusion: Cervical electrosurgical excision is an important diagnostic and therapeutic method for cervical intraepithelial neoplasia. It has great clinical value for the treatment of benign cervical lesions.