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目的观察剖宫产术中舌下含服米索前列醇联合静脉点滴缩宫素预防产后出血的效果。方法选择有发生产后出血高危因素的剖宫产产妇随机分为治疗组、对照组各100例。对照组单纯静脉滴注缩宫素10 U,治疗组在剖宫产术中胎儿娩出后舌下含服米索前列醇0.2 mg同时静脉点滴缩宫素10 U,观察两组用药后子宫出血量及宫底下降情况。结果对照组产妇产后30 min、2 h出血量分别为(396.9±40.2)ml、(488.7±82.6)ml,治疗组产妇产后30 min、2 h出血量分别为(214.5±45.3)ml、(359.1±83.4)ml;对照组产后2 h子宫底下降(16.2±1.5)cm,治疗组产后2 h子宫底下降(20.3±1.2)cm。结论舌下含服米索前列醇联合静脉点滴缩宫素促进子宫收缩明显,能很好地预防剖宫产产后出血且用药方便、安全。
Objective To observe the effect of sublingual misoprostol combined with intravenous oxytocin in preventing postpartum hemorrhage during cesarean section. Methods Cesarean section women who had the risk of postpartum hemorrhage were randomly divided into treatment group and control group with 100 cases each. Control group simply by intravenous infusion of oxytocin 10 U, the treatment group in the cesarean section after the fetus was delivered sublingual misoprostol 0.2 mg at the same time intravenous oxytocin 10 U, the two groups were observed after uterine bleeding And the bottom of the palace down situation. Results The amount of bleeding in the control group was (396.9 ± 40.2) ml and (488.7 ± 82.6) ml at 30 and 2 h postpartum, respectively. The bleeding volume in the treatment group was (214.5 ± 45.3) ml and ± 83.4) ml in the control group, while the control group descended (16.2 ± 1.5) cm at 2 h postpartum. The end of the uterus decreased 20.3 ± 1.2 cm in the control group 2 h postpartum. Conclusion Oral sublingual misoprostol combined with intravenous oxytocin to promote uterine contractions significantly, can prevent bleeding after cesarean section and medication convenient and safe.