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目的探讨原发性甲状腺功能亢进症合并甲状腺癌采用甲状腺全切除术治疗的临床效果。方法对2015年4月-2016年4月本院收治的66例原发性甲状腺功能亢进症合并甲状腺癌患者的一般资料进行回顾性分析,所有患者均经术前或术中病理检查,确诊为原发性甲状腺功能亢进症合并甲状腺癌。按照随机数字表法,将66例患者分为研究组(甲状腺全切除术)与对照组(患癌侧腺叶切除术加对侧腺叶次全切除术),对比两组治疗效果。结果两组手术时间、住院时间差异不显著(P>0.05);两组喉返神经损伤发生率差异不显著(P>0.05);研究组甲亢复发率、术后出血率均低于对照组,差异显著(P<0.05)。结论在原发性甲状腺功能亢进症合并甲状腺癌患者的临床治疗过程中,采用甲状腺全切术治疗的效果显著,能减少出血,降低复发率,且不会增加喉返神经损伤风险,值得进行深入研究和推广。
Objective To investigate the clinical effects of total thyroidectomy for primary hyperthyroidism complicated with thyroid cancer. Methods The data of 66 patients with primary hyperthyroidism complicated with thyroid cancer admitted to our hospital from April 2015 to April 2016 were retrospectively analyzed. All patients were diagnosed preoperatively or intraoperatively as pathological examination Primary hyperthyroidism with thyroid cancer. According to the random number table method, 66 patients were divided into the research group (total thyroidectomy) and the control group (with the cancer of the subtotal lobectomy and lobectomy), compared the two groups. Results There was no significant difference in operative time and hospital stay between the two groups (P> 0.05). There was no significant difference in the incidence of recurrent laryngeal nerve injury between the two groups (P> 0.05). The recurrence rate of hyperthyroidism and postoperative bleeding in the study group were lower than those in the control group The difference was significant (P <0.05). Conclusions In the clinical treatment of patients with primary hyperthyroidism complicated with thyroid cancer, the effect of total thyroidectomy is significant, which can reduce the bleeding and reduce the recurrence rate without increasing the risk of recurrent laryngeal nerve injury, which deserves further study Research and promotion.