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为研究氧化应激在葡萄糖对β细胞毒性中的意义 ,并寻找保护 β细胞免受这种毒性作用的办法 ,作者使用抗氧化剂治疗 ,研究其对糖尿病Ｃ5 7ＢＬ/ＫｓＪ ｄｂ/ｄｂ鼠 (一种常用的肥胖型 2型糖尿病动物模型 ) β细胞功能的保护作用。方法 6周龄Ｃ5 7ＢＬ/ＫｓＪ ｄｂ/ｄｂ鼠分为
To investigate the role of oxidative stress in glucose cytotoxicity against beta-cells and to find ways to protect beta cells against this toxic effect, the authors used anti-oxidant therapy to study the effects of glucose stress on C5 7BL / KsJ db / db mice Commonly used obese type 2 diabetic animal model) β-cell function of the protective effect. Methods 6 weeks old C5 7BL / KsJ db / db mice were divided