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犬用戊巴比妥钠麻醉,合成的牛甲状旁腺素包含34个氨基酸【bpTH-(1—34)】的氨基末端,剂量0.1～0.8μg/kg,静脉注射后可导致与剂量相关的动脉血压下降、心搏出量增加以及总外周阻力显著减小。明显增加腹腔、冠状和肾血流量,并降低这些器官中血管床的阻力。肠系膜和髂血流一般是减少的。肠系膜血管阻力的改变轻微,而髂血管阻力的增高显著。在动脉血压,已经恢复到对照水平时,肾血流量的增加还能明显地
Dogs were anesthetized with sodium pentobarbital and the synthetic bovine parathyroid hormone contained a 34 amino acid amino terminus [bpTH- (1-34)] at a dosage of 0.1-0.8 μg / kg, which resulted in dose-related Arterial blood pressure decreased, increased cardiac output and total peripheral resistance was significantly reduced. Significantly increased abdominal, coronary and renal blood flow, and decreased vascular bed resistance in these organs. Mesentery and iliac blood flow is generally reduced. Mesenteric vascular resistance changed slightly, while the iliac vascular resistance increased significantly. In the arterial blood pressure, has returned to the control level, the renal blood flow increased significantly