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肥胖疗法的核心是饮食疗法。但食欲是种族生存的本能,抑制食欲并非易事,因此,在饮食疗法不能很好实施的情况下,可采用辅助的药物和精神疗法。一、食欲抑制剂 1.苯丙胺(anphetamine)及其衍生物苯丙胺于19世纪末合成,20世纪30年代起临床用作为肥胖治疗药。Harris等发现,在给予苯丙胺的过程中,如摄取与对照组相同量的食物,则不会引起体重下降,因而认为该药的作用乃在于对食欲的抑制。其作用机制是能促进去甲肾上腺素自神经末梢的释放,使饱食中枢兴奋。苯丙胺的副作用有心悸、多汗、高血压等交感神经刺激症状以及烦躁不
The core of obesity therapy is diet therapy. But appetite is the instinct of racial survival, inhibition of appetite is not easy, so in the case of diet can not be well implemented, the use of complementary drugs and psychotherapy. First, the appetite suppressant 1. Amphetamine (anphetamine) and its derivatives amphetamine synthesis in the late 19th century, from the 1930s clinically used as a therapeutic drug for obesity. Harris et al. Found that in the course of giving amphetamines, the same amount of food as the control group did not cause weight loss, and therefore the drug’s action is believed to be appetite suppression. Its mechanism of action is to promote the release of norepinephrine from the nerve endings, excite the satiety center. Side effects of amphetamines are palpitations, hyperhidrosis, hypertension and other symptoms of sympathetic nerve irritation and irritability