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报告胰岛素瘤１８例，８例长期被误诊为癫痫（６例）或精神病（２例），误诊率高达４４４％。主要依据Ｗｈｉｐｐｌｅ三联征诊断。凡遇有精神病或癫痫样症状而治疗效果不明显的病人，即应疑及本病。术前经各种检查仍不能定位时，可根据临床表现行剖腹探查。最好行胰岛素瘤剜除术（ｅｎｕｃｌｅａｔｉｏｎ），必要时也可行胰十二指肠切除或胰体尾切除，但应尽量避免盲目性胰体尾及脾切除术。术后并发症为胰瘘、假性胰腺囊肿、腹腔脓肿。究其原因，可能是缝合创面过密，造成胰腺组织坏死脱落过多或胰管破裂所致
Reported 18 cases of insulinoma, 8 cases were misdiagnosed as epilepsy (6 cases) or mental illness (2 cases), misdiagnosis rate as high as 44.4%. Mainly based on the diagnosis of Whipple triad. Patients who have mental illness or epilepsy-like symptoms and have no obvious treatment effect should be suspicious of the disease. If the patient cannot be positioned before the operation through various examinations, laparotomy can be performed according to clinical manifestations. It is best to perform enucleation of insulinoma, and if necessary, pancreaticoduodenectomy or pancreatic body resection can be performed. However, blind pancreatic body and splenectomy should be avoided. Postoperative complications were pancreatic fistula, pseudo-pancreatic cyst, and abdominal abscess. The reason may be that the sutured surface is too dense, resulting in excessive necrosis of the pancreas or rupture of the pancreatic duct.