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作者观察了动脉粥样硬化家兔体内血脂代谢,血液流变学,MDA与SOD,6-酮基-PGF_(1α)与TXB_2,雌二醇与睾酮的变化及鞠泻片对其影响,结果发现病理组家兔血浆6-酮基-PGF_(1α)为 151.57±74.70 ng/L,TXB_2值为1166.63±554.70 ng/L。鞠泻片治疗组6-酮基-PGF_(1α)为187.60±70.43 ng/L,TXB_2值为270.10±120.40 ng/L,两值平衡恢复。病理组雌二醇为61.90±12.86 ng/L,睾酮值为51.90±44.54 ng/L,治疗组雌二醇为80.28±33.18 ng/L,睾酮值为 88.44±44.65 ng/L。鞠泻片使血脂MDA血粘度降低,提高体内SOD和激素水平,恢复6-酮-PGF_(1α)与TXB_2二者的平衡。
The authors observed changes in blood lipid metabolism, hemorheology, MDA and SOD, 6-keto-PGF_(1α) and TXB_2, estradiol and testosterone in atherosclerotic rabbits and their effects on diarrhea tablets. The plasma 6-keto-PGF_(1α) in the pathological group was found to be 151.57±74.70 ng/L, and the TXB_2 value was 1166.63±554.70 ng/L. The 6-keto-PGF_(1α) in the treatment group was 187.60±70.43 ng/L, and the TXB_2 value was 270.10±120.40 ng/L. The estradiol in the pathological group was 61.90±12.86 ng/L, the testosterone value was 51.90±44.54 ng/L, the estradiol in the treated group was 80.28±33.18 ng/L, and the testosterone value was 88.44±44.65 ng/L. Xie Xie Tablets reduce the blood viscosity of MDA blood, increase the levels of SOD and hormones in the body, and restore the balance of 6-keto-PGF_(1α) and TXB_2.