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很多研究指出,血清铜的含量与何杰金氏病的活动度有正相关。Jensen(1964)认为血清铜的变化比血沉灵敏。作者对54例病情活动的何杰金氏病患者进行了血清铜及血沉的测定和比较。正常对照组中女子150人,血清铜的含量为16～29μmol/L;男子38人,血清铜为13～26μmol/L。血沉正常值采用较高和年龄依赖的正常值,54例病人中,血清铜的含量及血沉各有38人增加,异常数值在该病的Ⅰ～Ⅱ期和Ⅲ～Ⅳ期出现频率相似;在组织学亚群,血清铜升高与血沉升高次数很接近。对78例病情稳定且完全缓解的何杰金氏病患者做了186次血清铜和血沉测定,发现总的测定次数中14%血清铜增高,16.5%血沉增高。比较血清铜和血沉的假阳性率时发现,在54例病情进展的患者中,有16人血沉不增高,其中5人由血
Many studies have pointed out that serum copper levels and Hodgkin’s disease activity has a positive correlation. Jensen (1964) that serum copper changes more sensitive than erythrocyte sedimentation rate. The authors of 54 cases of Hodgkin’s disease activity of serum copper and ESR were measured and compared. The normal control group of 150 women, the serum copper content of 16 ~ 29μmol / L; 38 men, serum copper 13 ~ 26μmol / L. The ESR values were normal and age-dependent. In 54 patients, the levels of serum copper and erythrocyte sedimentation rate were all increased in 38 patients. The frequency of abnormalities was similar between Ⅰ ~ Ⅱ and Ⅲ ~ Ⅳ of the disease. Histological subgroups, elevated serum copper and ESR number is very close. Of the 78 Hodgkin’s disease patients with stable and complete remission, 186 serum copper and ESR tests were performed and found that 14% serum copper increased and 16.5% ESR increased in the total number of tests. When comparing the false positive rates of serum copper and erythrocyte sedimentation rate, 16 of the 54 patients with progression-free disease did not have elevated ESR, of which 5 were blood