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本文研究葛根素对冠心病病人内皮素－１（ＥＴ－１）和血小板功能的影响。将４８例随机分为对照组与葛根素组，葛根素组加用葛根素注射液。结果是葛根素组血浆ＥＴ－１和血栓素Ｂ２在治疗后较治疗前显著下降（Ｐ＜０．０１），６－酮－前列腺素Ｆ１α高于治疗前（Ｐ＜０．０１），血浆内颗粒膜蛋白、血小板凝聚试验和血小板粘附试验较治疗前均有明显降低（Ｐ＜０．０１），表明葛根素具有降低血浆ＥＴ－１和血小板表面活性，抑制血小板聚集和粘附，抗血栓形成的作用。
This article studies the effect of puerarin on endothelin-1 (ET-1) and platelet function in patients with coronary heart disease. 48 cases were randomly divided into control group and puerarin group, puerarin group plus puerarin injection. As a result, plasma ET-1 and thromboxane B2 in the puerarin group were significantly decreased after treatment (P<0.01), and 6-keto-prostaglandin F1α was higher than before treatment (P<0.01). The granule membrane protein, platelet aggregation assay, and platelet adhesion assay were significantly lower than before treatment (P<0.01), indicating that puerarin can reduce plasma ET-1 and platelet surface activity, inhibit platelet aggregation and adhesion, and prevent thrombosis The role of formation.