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药物除口服粉剂外,都靠递药系统(Drugdelivery systems)供病人使用,七十年代以来着重研究脂质体作为药物的载体,希望能选择性地达到靶组织,尤其着重于抗癌药物脂质体的研究。一、什么是脂质体?脂质体是由磷脂、胆固醇的疏水性基因交互作用而构成的双层脂质膜,亲水基团位于膜的表面,疏水性基团位于膜的中间,每层脂膜之间有少量水液,一大片双脂膜连接成一个小球,叫做脂质体(Liposomes)或称脂微球(Ve-sicle)。可将大小不规则的大脂质体超声处理,
In addition to oral powders, the drugs are used by patients for drug delivery systems. Since the 1970s, liposomes have been studied as carriers of drugs in hopes of selectively reaching the target tissues, with a particular emphasis on the anticancer drug lipids Body research. First, what is the liposome? Liposomes by the phospholipid, cholesterol, hydrophobic gene interaction composed of bilayer lipid membrane, hydrophilic groups located on the membrane surface, the hydrophobic group located in the middle of the membrane, each There is a small amount of aqueous fluid between the lipid layers, and a large double lipid membrane is connected to form a small ball, called Liposomes or Ve-sicle. Large size liposomes can be sonicated,