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摘要对３０例视网膜脱离（ＲＤ）患者及１００名健康人进行了ＨＬＡⅠ类抗原检测，并结合临床表现进行分析，发现视网膜脱离患者ＨＬＡ－Ａ１、Ａ３１、Ｂ５、Ｂｗ４６四种抗原较正常对照组高（Ｐ＜０．０５）。在ＲＤ患者中上述四种抗原阳性者ＰＶＲ形成和手术失败率明显高于４种抗原阴性者（Ｐ＜０．０５）。而且４种抗原有２种以上抗原阳性者ＰＶＲ的发生率增高至９０％，手术失败率及视网膜脱离复发率也增至６０％。结果提示视网膜脱离患者ＰＶＲ形成同全身ＨＬＡ变化有一定关系。
Abstract HLA class I antigens were detected in 30 patients with retinal detachment (RD) and 100 healthy individuals and analyzed with clinical manifestations. It was found that the four antigens of HLA-A1, A31, B5 and Bw46 in patients with retinal detachment were higher than those in normal controls (P <0.05). The incidence of PVR formation and failure in the above four antigens in patients with RD were significantly higher than those of the four antigens (P <0.05). And 4 kinds of antigens more than 2 antigen-positive PVR increased the incidence of 90%, the failure rate of surgery and retinal detachment recurrence rate also increased to 60%. The results suggest that retinal detachment PVR formation and systemic changes have a certain relationship.