Simultaneous Spectrophotometric Determination of Four Components including Acetaminophen by Taget Fa

• 作 者: 张立庆
• 机 构: Shool of Biological and Chemical Engineering Zhejiang University of Science and Technology,,Hangzhou
• 出 处: Journal of Wuhan University of Technology(Materials Science
• 发表日期: 2007年03期
• 关键词: simultaneous overlapping satisfactory cough maleate overcome difficulty steps ab

UV Spectrophotometric Target Factor Analysis(TFA)was used for the simultaneous determination of four components(acetaminophen,guuaifenesin,caffeine,Chlorphenamine maleate)in cough syrup.The computer program of TFA is based on VC++language.The difficulty of overlapping of absorption spectra of four compounds was overcome by this procedure.The experimental results show that the average recovery of each component is all in the range from 98.9%to 106.8%and each component obtains satisfactory results without any pre-separation.

UV Spectrophotometric Target Factor Analysis (TFA) was used for the simultaneous determination of four components (acetaminophen, guuaifenesin, caffeine, Chlorphenamine maleate) in cough syrup. The computer program of TFA is based on VC ++ language. The difficulty of overlapping of absorption spectra of four compounds was overcome by this procedure. The experimental results show that the average recovery of each component is all in the range from 98.9% to 106.8% and each component as satisfactory results without any pre-separation.