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近20年来由于临床及免疫组织化学研究的进展,对以淋巴增生为特征的Sjōgren综合征的病因、发病机制有了新的概念。除了泪腺、涎腺受侵犯外,它也可累及皮肤、肺、肾、肌肉等器官,故有自身免疫外分泌脉病的名称提出,以更确切的描述本病的基本情况。随着理论及检验技术的进步,对本病的诊断也更加明确。以往凡临床上出现眼干、口干、结缔组织病这三病征的两项,一般即
In the recent 20 years, due to the progress of clinical and immunohistochemical studies, there is a new concept of the etiology and pathogenesis of Sjōgren syndrome characterized by lymphoid hyperplasia. In addition to lacrimal gland, salivary gland invasion, it can also affect the skin, lungs, kidneys, muscles and other organs, it is the name of autoimmune exocrine disease proposed to more accurately describe the basic situation of the disease. With the progress of theory and testing technology, the diagnosis of this disease is more clear. In the past, clinically there are two symptoms of dry eye, dry mouth and connective tissue disease. Generally speaking,