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以ＤｉｇｄＵＴＰ标记的１６ＳｒＲＮＡ及２３ＳｒＲＮＡ基因为探针，分析了八个血清群５４个血清型６４株国内外致病性钩端螺旋体参考株和２７株野生株染色体经限制性内切酶ＥｃｏＲⅠ消化后的ｒＲＮＡ基因限制性图谱。结果发现，９１株菌中共有５６个核糖核酸型（Ｒｉｂｏｔｙｐｅ，简称ＲＴ），除部分血清群中少数不同的血清型有相同的ＲＴ型外，大部分血清型都有独特的ＲＴ型，同一血清群往往拥有共同的核心片段；除黄疸出血群的黄疸出血型外，同一血清型的国内和国际参考株的ＲＴ型不相同；大多数野生株的ＲＴ和相应血清型国内参考株相同，差异也只表现为谱形上个别带型的缺少和增加，所研究的波摩那型野生株的ＲＴ型和国际参考株相同而和国内参考株不同
Using Dig dUTP labeled 16S rRNA and 23S rRNA gene as probe, 54 serotypes of 64 serogroups of eight serogroups from domestic and abroad were used to probe pathogenic Leptospira reference strains and 27 wild-type chromosomes were digested with restriction endonuclease EcoRI After rRNA gene restriction map. The results showed that there were 56 Ribotypes (RTs) in 91 strains of bacteria. Most of the serotypes had a unique RT pattern except for a few serotypes of the same serotype. The same serotype Groups often share a common core segment; the RT patterns of domestic and international reference strains of the same serotype are not the same except for the jaundice hemorrhagic jaundice hemorrhagic group; RT for most wild-type strains is the same as for the corresponding reference serotypes in domestic Only showed the absence and increase of individual bands in the spectrum. The RT type of the wild type Pomona that was studied was the same as the international reference strain but different from the domestic reference strain