论文部分内容阅读
目的对应用小剂量甲状腺素联合厄贝沙坦氢氯噻嗪治疗老年重症心力衰竭的临床效果进行研究。方法 88例老年重症心力衰竭患者,随机分为对照组和治疗组,每组44例。对照组患者采用厄贝沙坦氢氯噻嗪实施治疗,治疗组患者采用小剂量甲状腺素与厄贝沙坦氢氯噻嗪联合实施治疗。对比两组治疗效果。结果对照组患者治疗后(10.84±3.21)d心功能相关指标水平恢复正常,药物治疗时间(16.93±4.15)d;治疗组患者治疗后(7.78±2.15)d心功能相关指标水平恢复正常,药物治疗时间(12.39±4.13)d;两组心功能相关指标水平恢复时间和药物治疗时间比较差异均有统计学意义(P<0.05)。治疗组治疗总有效率为90.9%,高于对照组的70.5%(P<0.05)。对照组患者在治疗期间有7例药物不良反应出现,治疗组患者在治疗期间有1例药物不良反应出现,两组比较差异有统计学意义(P<0.05)。结论应用小剂量甲状腺素联合厄贝沙坦氢氯噻嗪,对患有重症心力衰竭疾病的老年患者的临床效果非常明显。
Objective To study the clinical effect of low-dose thyroxine combined with irbesartan hydrochloride in elderly patients with severe heart failure. Methods 88 cases of elderly patients with severe heart failure were randomly divided into control group and treatment group, 44 cases in each group. Control group patients with irbesartan hydrochlorothiazide implementation of treatment, the treatment group of patients with small doses of thyroxine and irbesartan hydrochlorothiazide combination therapy. Compare the two groups treatment effect. Results In the control group, the cardiac function-related index returned to normal after treatment (10.84 ± 3.21), the duration of drug treatment was (16.93 ± 4.15) days; the cardiac function-related index returned to normal after treatment in the treatment group (7.78 ± 2.15) (12.39 ± 4.13) d. There was significant difference between the two groups in the recovery time of cardiac function-related index and the time of drug treatment (P <0.05). The total effective rate of treatment group was 90.9%, higher than 70.5% of control group (P <0.05). In the control group, 7 cases of adverse drug reactions occurred during the treatment. One case of adverse drug reactions occurred in the treatment group during the treatment period. The difference between the two groups was statistically significant (P <0.05). Conclusion The application of low dose of thyroxine combined with irbesartan hydrochloride in elderly patients with severe heart failure has obvious clinical effect.