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目的探讨阿托伐他汀对进展性脑梗死神经功能的影响。方法本组病例来自2008年1月—2010年1月收治的进展性脑梗死216例,随机分为常规治疗组100例,阿托伐他汀组116例,观察两组神经功能评分变化和血脂变化。结果经统计学分析,两组病例进行神经功能评分比较P<0.05有显著差异性。两组治疗前血脂比较P>0.05无显著差异性。两组治疗后血脂比较P<0.05有显著差异性。结论治疗进展性脑梗死中应用阿托伐他汀能够有效的改善和促进神经功能恢复,促进疾病的康复,明显降低血脂浓度,防止脉粥样硬化斑块破裂,减轻血栓形成反应。
Objective To investigate the effect of atorvastatin on neural function in patients with progressive cerebral infarction. Methods A total of 216 patients with progressive cerebral infarction who were admitted to our hospital from January 2008 to January 2010 were randomly divided into routine treatment group (n = 100) and atorvastatin group (n = 116). The changes of neurological score and blood lipid . Results By statistical analysis, two groups of patients with neurological scores were significantly different P <0.05. Two groups before treatment lipids compared P> 0.05 no significant difference. Two groups of blood lipid after treatment P <0.05 significant difference. Conclusions The use of atorvastatin in the treatment of progressive cerebral infarction can effectively improve and promote the recovery of neurological function, promote the recovery of the disease, significantly reduce the blood lipid concentration, prevent the rupture of atherosclerotic plaque and reduce the thrombosis reaction.