论文部分内容阅读
目的:探讨对糖尿病前期(IGR)人群经综合性、个体化方案干预后的转归。方法:怒江社区IGR自愿参加本研究的125人进行20个月综合干预;使用统一调查表;干预前后检测血糖、糖耐量试验(75 gOGTT)、空腹胰岛素及C肽和糖化血红蛋白。干预措施为健康教育和提供个体化饮食、运动方案及定期监测。结果:干预回访率高达100%,38人血糖逆转至正常血糖,逆转率为30.4%;干预后空腹血糖、OGTT 120分血糖分别下降,其结果经检验差异有统计学意义(P<0.05);空腹胰岛素、空腹C肽值均上升,其结果经检验差异有统计学意义(P<0.05);HbA1c平均水平干预前后,经检验差异无统计学意义(P>0.05)。结论:IGR人群经社区卫生服务进行综合性、个体化的干预措施可改善其转归,但结果与其依从性有关。
Objective: To investigate the prognosis of pre-diabetic (IGR) population after intervention of comprehensive and individualized programs. Methods: 125 volunteers from IGR volunteered to participate in the comprehensive intervention for 20 months in Nujiang community. A questionnaire was used to measure blood glucose, glucose tolerance test (75 gOGTT), fasting insulin, C-peptide and HbA1c before and after intervention. Interventions provide health education and provide individualized diets, exercise programs and regular monitoring. Results: The rate of follow - up visits was as high as 100%. The blood glucose of 38 people reversed to normal blood glucose with a reversal rate of 30.4%. After fasting, fasting blood glucose and OGTT 120 blood glucose decreased respectively. The difference was statistically significant (P <0.05). Fasting insulin, fasting C peptide values were increased, the test results showed that the difference was statistically significant (P <0.05); HbA1c average level before and after intervention, the test showed no significant difference (P> 0.05). Conclusion: The comprehensive and individualized interventions of IGR population in community health service can improve their outcomes, but the results are related to their compliance.