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目的：探求慢性粒细胞白血病加速期的新治疗方案。方法：分别采用中西医结合治疗（治疗组２５例）与单纯西药治疗（对照组２０例）成人慢性粒细胞白血病加速期患者，观察比较临床疗效及其骨髓象、血象的变化。结果：治疗组在发热、出血、骨痛等症状缓解及脾脏缩小、白细胞总数下降等方面疗效明显优于对照组，且能推迟病情向急变期演变，延长了生存期。结论：中西医结合治疗慢性粒细胞白血病加速期为传统药物治疗无效的病例增加了一种新的治疗方案，但不能阻止其向急变期演变的最终结局
Objective: To explore a new treatment plan for the accelerated phase of chronic myelogenous leukemia. METHODS: Patients with chronic myelocytic leukemia at an accelerated stage were treated with integrated Chinese and Western medicine (25 cases in the treatment group) and western medicine alone (20 cases in the control group). The clinical efficacy and changes of bone marrow and blood were observed and compared. RESULTS: The therapeutic effect of the treatment group was better than that of the control group in terms of remission of fever, bleeding, bone pain, reduction of the spleen, and decrease of the total number of white blood cells. It was able to delay the evolution of the disease to the blast crisis and prolong the survival period. Conclusion: The combination of TCM and west medicine in the accelerated phase of chronic myeloid leukemia is a new treatment option for cases ineffective for traditional drug treatment, but it can not stop the final outcome of its evolution to blast phase.