论文部分内容阅读
目的探讨高龄肺癌患者预后的影响因素,为高龄肺癌患者的诊断和治疗提供依据。方法回顾性分析98例高龄肺癌患者的临床资料,对患者的性别、功能状态(PS)评分、病理类型、临床分期、是否早期手术、晚期化疗方式以及是否接受放射治疗等因素与生存时间进行单因素分析,对分析结果有统计学意义的因素再进行多因素回归分析。结果 PS评分、临床分期、早期手术和晚期化疗方式与患者的生存时间相关(P<0.05)。多因素回归分析结果显示,PS评分和临床分期是高龄肺癌患者独立的预后危险因素。结论 PS评分和临床分期影响高龄肺癌患者的预后,对PS评分高的患者建议手术治疗,PS评分低的患者建议采取最佳支持治疗。
Objective To investigate the influencing factors of prognosis in elderly patients with lung cancer and provide evidence for the diagnosis and treatment of elderly patients with lung cancer. Methods The clinical data of 98 elderly patients with lung cancer were retrospectively analyzed. The patients’ gender, functional status (PS) score, pathological type, clinical stage, whether early surgery, late chemotherapy and whether to accept radiotherapy and survival time were retrospectively analyzed Factor analysis, the analysis of the results were statistically significant factors further multi-factor regression analysis. Results PS score, clinical stage, early surgery and late chemotherapy were related to the survival time (P <0.05). Multivariate regression analysis showed that PS score and clinical stage were independent prognostic risk factors for advanced lung cancer patients. Conclusion PS score and clinical stage affect the prognosis of elderly patients with lung cancer. Patients with high PS score are recommended for surgery and patients with low PS score are recommended to take the best supportive care.