论文部分内容阅读
成人T细胞白血病(ATL),多发生于以日本九州、南四国、南边沿海岸附近为中心的偏僻地区,是具有特殊的临床表现的新疾病,目前已被公认。ATL在多发地区40岁以上的成人中常见,预后非常坏,目前的抗癌制剂无效,几乎所有的患者均在发病2年内死亡。最近,日沼等发现了一种逆转录病毒为ATL的病因,命名为成人T细胞白血病病毒(ATLV)。根据日沼等人的研究,证实了几乎全部ATL患者的血清中,存在ATLV抗体。即使在健康人血清中,也存在ATLV抗体。长崎大学医学部动物学教研室曾调查了长崎县五岛的2个村,20岁以上健康成人ATLA抗
Adult T-cell leukemia (ATL), which occurs mostly in remote areas centered around Kyushu, Nankoku and the southern coast of Japan, is a new disease with special clinical manifestations and is now well established. ATL is common in adults over the age of 40 in multiple locations and has a very poor prognosis. The current anti-cancer agents are ineffective and almost all patients die within 2 years of onset. Recently, Nippon Marsh found a retrovirus is the cause of ATL, named adult T cell leukemia virus (ATLV). According to research by Nikuma et al, it was confirmed that ATLV antibodies were present in sera of almost all patients with ATL. Even in healthy human serum, ATLV antibodies are present. Department of Zoology, Nagasaki University School of Medicine Department of Zoology Has investigated two villages in Nagasaki Ward, 20 years of age healthy adults ATLA anti