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近年来,随着高能放疗没备的普及和综合治疗手段的开展,鼻咽癌的治愈率逐渐提高,患者生存期明显延长。但是,放疗后远期的照射效应则更多地表现出来,尤其是内分泌方面的并发症,严重影响患者身心健康,降低了生存质量,已受到人们的重视。本文就有关鼻咽癌放射治疗后出现下丘脑-垂体轴的损伤作一简述。一、下丘脑-垂体轴(HPA)的细胞学及病理变化下丘脑是人体间脑内的一个狭小的解剖部位,在内
In recent years, with the popularization of high-energy radiotherapy and the development of comprehensive treatment methods, the cure rate of nasopharyngeal cancer has gradually increased, and the survival period of patients has been significantly extended. However, the long-term radiation effects after radiotherapy are more manifested, especially the endocrine complications, which seriously affect the physical and mental health of patients and reduce the quality of life, which has received people’s attention. This article briefly discusses the injury of the hypothalamus-pituitary axis after radiotherapy for nasopharyngeal carcinoma. First, the cytology and pathological changes of the hypothalamus-pituitary axis (HPA) The hypothalamus is a narrow anatomy in the brain between the human body, including