论文部分内容阅读
一氧化氮(NO)是一种多能气态自由基,存在于身体的各个组织中。在肝脏,一氧化氮具有重要作用及不同的细胞来源。由于一氧化氮在正常组织和细胞中的确切作用较复杂,而且每一种细胞来源都很重要,一氧化氮在肝内的作用显得尤其令人困惑。自从1987年证实血管内皮衍生舒张因子(EDRF)的化学本质为一氧化氮以来,对于一氧化氮研究多年,人们得出的实验结果却是矛盾的:即对于正常的生理调节,一氧化氮的确发挥作用;但在细胞和组织损伤中,一氧化氮对损伤的进展同样
Nitric oxide (NO) is a potent gaseous free radical found in various tissues of the body. In the liver, nitric oxide has an important role and different sources of cells. Since the exact role of nitric oxide in normal tissues and cells is complex and each cell source is important, the role of nitric oxide in the liver is particularly puzzling. Since the chemical nature of EDRF has been demonstrated to be nitric oxide since 1987, experimental results for years of research on nitric oxide have contradictory: that for normal physiological regulation, nitric oxide is indeed Play a role; but in cell and tissue damage, the same progression of damage to nitric oxide