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常规的化疗和放疗只能稍延长本病的病程,且70%以上的病例死于急性变。本文报导选择性脾切除对本病在延迟急性变的发生和病程延长的影响。方法:病例26例,男15例,女11例。年龄16~64岁。均具有本病的典型临床和血液学表现,在骨髓和或脾发现Ph~1染色体。接受治疗的条件:①确诊为本病的慢性期;②临床和血液学对原先的治疗反应良
Conventional chemotherapy and radiotherapy can only slightly prolong the course of the disease, and more than 70% of the cases died of acute change. This article reports the effect of selective splenectomy on the occurrence and duration of delayed acute degeneration. Methods: 26 cases, 15 males and 11 females. Age 16 ~ 64 years old. Have the typical clinical and hematological manifestations of the disease, found in the bone marrow and or spleen Ph ~ 1 chromosome. Conditions for treatment: ① diagnosed as chronic disease; ② clinical and hematology on the original response to treatment