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人PBMC在体内与IL_2共孵,可产生杀伤新鲜自身瘤细胞(LAK),后者也能溶解新鲜同种异体瘤细胞及耐NK溶解的建株瘤细胞.小鼠脾细胞经IL_2刺激也能产生LAK.移植肿瘤的小鼠,注射IL_2并被动输注LAK
Human PBMCs are incubated with IL-2 in vivo, which can kill fresh self-tumor cells (LAK), which can also dissolve fresh allogeneic tumor cells and NK-resistant tumor cells. IL-2 stimulated mouse splenocytes also Tumors were generated in LAK. Mice were injected with IL-2 and infused with LAK infusively