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24名可卡因瘾患者,至少用可卡因已有6个月,每周3次,直到研究开始。治疗前1个月不用其它药物。受试者随机分成两组,第一组接受溴隐亭0.625 mg,每日4次,共42天。第二组接受葡萄糖作为安慰剂,每日4次,天数相同。用简便精神病评价指数(BPRS)评价患者。试验结果表明,两组间有明显差异(P<0.001),溴隐亭治疗组戒断症状改善明显(P<.0001)。作者认为,溴隐亭可有效地减轻可卡因嗜欲和戒断开始的焦虑症状,其作用机
Twenty-four patients with cocaine addiction had been using cocaine for at least 6 months three times per week until the study was started. 1 month before treatment without other drugs. Subjects were randomized into two groups. The first group received bromocriptine 0.625 mg four times a day for a total of 42 days. The second group received glucose as a placebo 4 times a day for the same number of days. Patients were evaluated using the Simple Mental Illness Index (BPRS). The results showed that there was a significant difference between the two groups (P <0.001), and bromocriptine treatment group significantly improved withdrawal symptoms (P <.0001). The author believes that bromocriptine can effectively alleviate the cramps of cocaine cramps and withdrawal symptoms, the role of machine