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测定34例肝硬化,23例正常人血清锌含量,结合透明质酸和肝功能储备Child-Pugh分级评分指标分析,显示肝硬化组血锌明显降低,以B,C级组尤为显著,与正常对照比较,差别具有显著性。透明质酸随肝功能储备下降而明显增高,各组间差别均显著。血锌降低与透明质酸增高呈负相关,与Child-Pugh评分呈负相关。研究结果表明,肝硬化肝功能储备降低伴有锌缺乏,补锌对肝硬化可能有治疗意义。
Determination of 34 cases of cirrhosis, 23 cases of normal serum zinc levels, combined with hyaluronic acid and liver function reserve Child-Pugh grading index analysis showed that liver cirrhosis group significantly decreased blood zinc to B, C group was particularly significant, with normal The differences were significant. Hyaluronic acid decreased significantly with the decline of liver function reserve, the differences between the groups were significant. Zinc deficiency was negatively correlated with increased hyaluronic acid and negatively correlated with Child-Pugh score. The results show that the reduction of liver function reserve of liver cirrhosis with zinc deficiency, zinc supplementation may have therapeutic significance for cirrhosis.