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为了了解肌肉注射蒿甲醚对重症恶性疟患儿原虫存活力的影响,于1993年6至11月在肯尼亚沿海的Kilifi区医院的肯尼亚医学研究所进行了蒿甲醚与奎宁治疗重症恶性疟过程中原虫存活力的体外培养评估。 对象系来自该医院入院确诊的脑型疟患儿,原虫感染红细胞在2％以上,除氯喹外未接受任何其它抗疟药且能配合试验者,征得家长同意后随机分为两组,各7名。奎宁组首剂20mg/kg静脉滴注(持续4小时),后改为
In order to understand the effect of intramuscular artemether on the viability of protozoa in children with severe falciparum malaria, artemether and quinine were administered to Kenyan Medical Institute in Kilifi District Hospital, Kenya, from June to November 1993 to treat severe falciparum malaria Evaluation of protozoa viability in vitro culture in vitro. Subjects from the hospital admitted to hospital diagnosed cerebral malaria children, protozoa infected red blood cells in more than 2%, except for chloroquine did not receive any other antimalarial drugs and can cooperate with the test, with the consent of the parents were randomly divided into two groups, each Seven. Quinine group first dose 20mg / kg intravenous infusion (for 4 hours), later changed to