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目的探讨急性黄磷中毒的临床诊治措施及发病机制。方法选择1998年9月—2012年11月收治的24例急性黄磷中毒住院患者,从临床表现、诊治经过作回顾性分析,并探讨其发病机制及采取相应干预措施。结果24例患者23例痊愈出院,治愈率为95.8%,1例并发心肺肝胃肠肾脑血液衰竭自动出院。结论急性黄磷中毒主要损害的器官是肺脏,积极治疗肺水肿,修复损伤支气管黏膜,纠正缺氧,改善肺功能是阻断病情发展的关键。
Objective To investigate the clinical diagnosis and treatment of acute yellow phosphorus poisoning and its pathogenesis. Methods Twenty-four inpatients with acute yellow phosphorus poisoning admitted from September 1998 to November 2012 were retrospectively analyzed from the clinical manifestations, diagnosis and treatment, and their pathogenesis were investigated. Results Twenty-four patients were cured and discharged from hospital. The cure rate was 95.8%. One patient was discharged spontaneously with cardiopulmonary, hepatic, renal, and renal failure. Conclusion The main organ damage caused by acute yellow phosphorus poisoning is the lung. Active treatment of pulmonary edema, repair of damaged bronchial mucosa, correct hypoxia, and improve lung function are the key points to stop the progression of the disease.