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目的对比分析慢性阻塞性肺疾病合并呼吸衰竭采用无创正压机械通气联合缩唇膈式呼吸功能锻炼的临床效果。方法选取慢阻肺合并呼吸衰竭患者共110例。随机分为观察组和对照组各55例。观察组患者采用无创正压机械通气联合缩唇膈式呼吸进行治疗,对照组仅给予无创正压机械通气治疗,两组患者连续治疗10d对比分析两组患者血p H值、Pa O2、Pa CO2和呼吸肌功能指标评定临床治疗效果。结果两组患者治疗10d后血PH值、Pa O2、Pa CO2、最大吸气压(MIP)、平均跨膈压(Pdi)均有一定程度的改善,观察组改善程度显著优于对照组(P<0.05)具有统计学意义。结论对于慢阻肺合并呼吸衰竭患者来说,联合应用无创正压机械通气和缩唇膈式呼吸功能锻炼能够明显改善肺通气功能,并不加重呼吸肌疲劳,能够早期改善临床症状,利于患者恢复。
Objective To compare and analyze the clinical effect of noninvasive positive pressure mechanical ventilation in combination with reduced-lip diaphragm breathing exercise in chronic obstructive pulmonary disease with respiratory failure. Methods A total of 110 patients with chronic obstructive pulmonary disease and respiratory failure were selected. Randomly divided into observation group and control group of 55 cases. Patients in the observation group were treated with noninvasive positive pressure mechanical ventilation combined with deflated lip respiration, while those in the control group were treated with noninvasive positive pressure mechanical ventilation. The blood p H value, Pa O2 and Pa CO2 were compared between the two groups after 10 days of continuous treatment And respiratory muscle function indicators to assess the clinical effect. Results After 10 days of treatment, PH, Pa O2, Pa CO2, MIP and Pdi in both groups improved to a certain extent, and the improvement in the observation group was significantly better than that in the control group <0.05) with statistical significance. Conclusions For COPD patients with respiratory failure, the combined use of non-invasive positive pressure mechanical ventilation and lip-narrow breathing exercises can significantly improve pulmonary ventilation, does not aggravate respiratory muscle fatigue, and can improve clinical symptoms in the early stage, which will benefit patients to recover .