Malaria still remains one of the major public health problems all over the world[1].Although artemisinin has been used successfully against chloroquine-resi
In order to expand the structure-activity relationship(SAR) studies on arylazolylthioacetanilide NNRTIs [1-14],based on the structure-based bioisosterism pr
Heat shock protein 90 (Hsp90) is a recently recognized important target of cancer chemotherapy.Nearly 20 small molecule Hsp90 inhibitors are currently under
The occurrence of highly pathogenic avian influenza virus H5N1 highlights the urgent need for new classes of antiviral drugs.Theoretically,each of steps in