【摘 要】
：
In order to expand the structure-activity relationship(SAR) studies on arylazolylthioacetanilide NNRTIs [1-14],based on the structure-based bioisosterism pr
【机 构】
：
Department of Medicinal Chemistry,Key Laboratory of Chemical Biology of Natural Products(Ministry of
【出 处】
：
第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会
论文部分内容阅读
In order to expand the structure-activity relationship(SAR) studies on arylazolylthioacetanilide NNRTIs [1-14],based on the structure-based bioisosterism principle,a series of novel 2-(5-(naphthalen-1-yl)-1,2,3-thiadiazol-4-ylthio)-N-acetamides derivatives were designed,synthesized and evaluated for their anti-HIV activities in MT-4 cells.
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