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金属硫蛋白(metallothionein,MT)是一类低分子量(约6.5kD)富含半胱氨酸的金属结合蛋白。虽然现已发现MT广泛存在于哺乳动物多种组织中,但目前多采用组织匀浆提取MT后借助有关生化手段进行检测。潘爱华和陈吉龙对MT在大鼠几种组织细胞中的确切定位进行了研究。Onosaka等测定表明人脾脏中含有MT,对于MT在脾中的确切定位仍不清楚。此外,引人注目的是MT基因的诱导性,即在重金属或糖皮质激素等因素的诱导
Metallothionein (MT) is a class of low-molecular-weight (about 6.5 kD) cysteine-rich metal-binding proteins. Although MT has been found in a wide range of mammalian tissues, but the current use of tissue homogenate after the extraction of MT by means of biochemical tests. Pan Aihua and Chen Jilong on MT in several tissue cells in the exact location were studied. Onosaka et al. Showed that the presence of MT in human spleens remains unclear for the exact location of MT in the spleen. In addition, attracting attention is the induction of the MT gene, that is, induction of factors such as heavy metals or glucocorticoids