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二、临床症状感染贝纳氏立克次体可引起急性全身性疾病,表现为突发性不适、寒战、发热、肌肉酸痛和剧烈的头痛。甚至在退热后仍感虚弱和疲倦达数周或数月之久。Q热的临床诊断是困难的,因其症状与流感、急性布鲁氏菌病、伤寒或支原体性肺炎相类似。本病使人极感虚弱,在高加索人中死亡率估计低于1％。根据Derrick在Brisbane(澳大利亚)对237例诊断为Q热的病例的综述,将本病分为三个期。1.潜伏期:Q热的潜伏期约13～37天,平均19～20天。Tigertt对志愿者经呼吸道途径进行实验性感染,用10个ID_5o豚鼠感染剂量的志原感染者潜伏期为17天,使用15000～150000个ID_5o的感染者潜伏期为10
Second, clinical symptoms Infection rickettsiae can cause acute systemic diseases, manifested as sudden discomfort, chills, fever, muscle soreness and severe headache. Weakness and tiredness even after cooling for weeks or months. Clinical diagnosis of Q fever is difficult because its symptoms are similar to flu, acute brucellosis, typhoid or mycoplasma pneumonia. The disease makes one extremely weary, with an estimated mortality rate of less than 1% among Caucasians. According to Derrick’s review of 237 cases of diagnosed Q fever in Brisbane (Australia), the disease was divided into three phases. 1. Latency: Q hot incubation period of about 13 to 37 days, an average of 19 to 20 days. Tigertt conducted an experimental infection of volunteers via the respiratory tract. The incubation period of Chih-Yuan patients infected with 10 ID_5o guinea pigs was 17 days. The incubation period of those infected with 15,000-1500,000 ID_5o was 10