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利用Pd(O)催化下R~2R~3P(O)H(R~2,R~3=烷基、芳基、烷氧基)与芳基溴,烯基溴以及丁二烯反应合成芳基、烯基和烯丙基膦酸酯近年来有较多报道,但后者产率仅为10%。Fiaud曾报道了二苯基膦锂和醋酸烯丙酯的反应,但烯丙基膦化合物产率低于15%。我们曾发现醋酸烯丙酯在O,N-二(三甲硅基)乙酰胺(BSA)存在下,用Ni(cod)_3为催化剂与亚磷酸二酯反应,高产率地得到了烯丙基膦酸酯,而Pd(PPh_3)_4不能催化这个反应。我们认为反应的关键是亚磷酸二酯首先与BSA反应生成O,O-二烷基-O-三甲硅基亚磷酸酯
The synthesis of aryl (II) with aryl bromine, alkenyl bromine and butadiene by the reaction of R 2 R 3 P (O) H (R 2, R 3 = alkyl, aryl and alkoxy) Base, alkenyl and allyl phosphonates have been reported more in recent years, but the yield of the latter is only 10%. Fiaud reported the reaction of lithium diphenylphosphate with allyl acetate, but yields of allylphosphine compounds of less than 15%. We have found that allyl acetate can react with phosphite diester in the presence of O, N-bis (trimethylsilyl) acetamide (BSA) with Ni (cod) 3 as a catalyst to obtain allyl phosphine Acid ester, Pd (PPh_3) _4 can not catalyze this reaction. We think the key to the reaction is that the phosphite diester first reacts with BSA to form O, O-dialkyl-O-trimethylsilyl phosphite