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目的提出织纹螺中河豚毒素的限量建议值,为日常监控提供判定依据。方法对织纹螺中河豚毒素的来源、含量情况、毒性、检测标准以及国内外有关河豚毒素、麻痹性贝类毒素的规定等文献资料进行分析比较,探讨织纹螺中河豚毒素的限量要求。结果织纹螺可分为有毒织纹螺、无毒织纹螺、季节性有毒织纹螺,织纹螺中河豚毒素的浓度范围为0～177 mg/kg,而且河豚毒素毒性是麻痹性贝类毒素的30倍以上(以两者对小鼠的经口LD50比较)。对光织纹螺、正织纹螺等常年带毒且毒素含量高的有毒织纹螺应有效识别并禁止采捕、销售、食用,建议无毒织纹螺和季节性有毒织纹螺中河豚毒素的限量为0.05 mg/kg,测定方法采用GB/T 23217—2008《水产品中河豚毒素的测定》。结论提出织纹螺中河豚毒素的限量建议值应合理可行,有效地完善了织纹螺中河豚毒素的监控体系,保障广大公众的身体健康与生命安全。
OBJECTIVE: To propose the limited recommended value of tetrodotoxin in the snail and to provide the basis for daily monitoring. Methods The sources, content, toxicity, detection standards of tetrodotoxin in the snail and the domestic and international references on the regulations of tetrodotoxin and paralytic shellfish toxins were analyzed and compared to discuss the limited requirements of tetrodotoxin in snails. Results Conch can be divided into toxic snail, non-toxic snail, seasonal snail snail, snail venom toxin concentration range 0 ~ 177 mg / kg, and tetrodotoxin toxicity is paralytic shellfish Toxoid more than 30 times (as compared to the oral LD50 of mice). The light snail snail, snail and other perennial poisoning and high toxin content poisonous snails should effectively identify and prohibit the capture, sale, consumption, recommended non-toxic snails and seasonal poisonous snails puffer fish The toxin limit is 0.05 mg / kg. The determination method adopts the determination of tetrodotoxin in aquatic products according to GB / T 23217-2008. Conclusion The proposed limit value of tetrodotoxin in the snail should be reasonable and feasible, effectively improve the monitoring system of tetrodotoxin in snail, and ensure the public health and life safety.