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采取多种无创性检查(ECG、WFBE、STI、ACG、PCG、ICG、UCG等),对30例临床确诊为肌营养不良症(MD)患者和62名健康人(正常对照组),进行心功能检查,结果显示MD患者虽然早期无明显心血管症状,但反映舒张功能的主要指标。如PAWP、LVEDP、P/V、V/P、a/E-O、S_2O、SFW/RFW等均有不同程度的异常(与正常对照组比较,P<0.01)。心功能受累的程度与临床类型和病程有关,Duchenne型MD患者较肢带型的心肌受累更严重,前者不但舒张功能均有异常,且83.3%的患者收缩功能也有不同程序受累。
A total of 30 patients with muscular dystrophy (MD) and 62 healthy controls (normal control group) were enrolled in this study. They were treated with various noninvasive tests (ECG, WFBE, STI, ACG, PCG, ICG, Functional tests, the results showed that although patients with MD early no significant cardiovascular symptoms, but reflect the main indicators of diastolic function. Such as PAWP, LVEDP, P / V, V / P, a / E-O, S_2O, SFW / RFW and so have different degrees of abnormalities (compared with the normal control group, P <0.01). The extent of heart function involvement was related to the clinical type and course of disease. Duchenne type MD patients had more severe myocardial involvement than limb type. The former not only had abnormal diastolic function, but also had different procedures in 83.3% of patients.