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1951年 Austin 曾推测,耥子似乎需要在雌性生殖管道度过一些时间才能穿入卵的透明带。次年,该氏又指出,精子在具备穿入卵子的能力之前,必定要经过某种形式的生理学改变或“获能”,从而提出了精子获能这一概念。研究精子获能有许多方法。1955年张明觉把射出精子、附睾精子和在交配后不同时间从子宫内取得的精子输入排卵后不久的兔输卵管,结果发现只有从子宫内取出的精子能使兔卵受精;这表明获能可在子宫中完成。进一步的实验揭示,从兔子宫中取出的已获能精子,用5～20%的兔、牛或人的精浆液处理,可使之“去获能”,而去获能的精子在输卵管中还可以“再获能”。
In 1951, Austin had speculated that prickly heat seemed to need to spend some time in the female reproductive duct to penetrate the zona pellucida. The following year, the scholar also pointed out that sperm must undergo some form of physiological change or “empowerment” before they have the ability to penetrate the egg, thereby proposing the concept of sperm capacitation. There are many ways to study sperm capacitation. In 1955, Zhang injects the sperm into the sperm, the epididymal sperm and the sperm taken from the womb at different times after mating into the fallopian tube of the rabbit shortly after ovulation. As a result, only the sperm removed from the uterus can fertilize the rabbit egg; Complete the womb. Further experiments revealed that the sperm that has been removed from the uterus of the rabbit can be “de-energized” by treatment with 5-20% of seminal fluid of a rabbit, cow or human while the disabled sperm are harvested in the fallopian tubes You can also “re-energy.”