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实验观察经方附子汤对心血管系统6项指标的影响,结果证明,附子汤原方具有明显对抗心肌缺血、缺氧的能力,并能显著增加心肌营养血流量;降低红细胞膜的脂区微粘度;提高心肌细胞内环核苷酸的水平,其提高cAMP的作用大于对cGMP的作用,但cAMP/cGMP的值没有明显改变,该方还通过降低血栓素B_2的水平使6—酮—前列腺素F_1α/血栓素B_2的值明显升高,反映了抑制血小板聚集的作用。方中5味药在不同的方面发挥各自的作用,使原方配伍注意阴、阳、气、血的全面调整。全方的各项作用均大于拆方。参、附相伍作用突出,芍药配伍效应最强。
The experimental observation of the effect of the prescription of the Aconite Decoction on the six indicators of the cardiovascular system, the results show that the Aconite Tangyuan Decoction has obvious anti-ischemic and hypoxic ability, and can significantly increase the nutrient blood flow; reduce the red cell membrane lipid viscosity Increase the level of cyclic nucleotides in cardiomyocytes, its effect of increasing cAMP is greater than the effect of cAMP, but the value of cAMP/cGMP does not change significantly, this side also makes 6-keto-prostaglandin by reducing the level of thromboxane B 2 . The value of F_1α/thromboxane B 2 was significantly increased, reflecting the inhibition of platelet aggregation. Fangzhong 5 taste drugs play their own roles in different aspects, so that the original compatibility of Yin, Yang, gas, blood and full adjustment. The role of all parties is greater than disassembled parties. Participate in the role of ginseng and vasoconstrictor, and the compatibility of peony is the strongest.